prof. RNDr. Daniel Růžek, Ph.D.

2020

• FDA-Approved Drugs Efavirenz, Tipranavir, and Dasabuvir Inhibit Replication of Multiple Flaviviruses in Vero Cells

  ŠTEFÁNIK Michal VALDES James J. EZEBUO Fortunatus C. HAVIERNIK Jan UZOCHUKWU Ikemefuna C. FOJTÍKOVÁ Martina SALÁT Jiří EYER Luděk RŮŽEK Daniel

  Article in Periodical

  Microorganisms, year: 2020, volume: 8, edition: 4, DOI

• Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals

  SALÁT Jiří MIKULÁŠEK Kamil LARRALDE Osmany POKORNÁ FORMANOVÁ Petra CHRDLE Aleš HAVIERNIK Jan ELSTEROVÁ Jana TEISLEROVÁ Dana PALUS Martin EYER Luděk ZDRÁHAL Zbyněk PETRIK Juraj RŮŽEK Daniel

  Article in Periodical

  Vaccines, year: 2020, volume: 8, edition: 1, DOI

2019

• An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice

  EYER Luděk NOUGAIREDE Antoine UHLÍŘOVÁ Marie DRIOUICH Jean-Sélim ZOUHAROVÁ Darina VALDÉS James J. HAVIERNIK Jan GOULD Ernest A. DE CLERCQ Erik DE LAMBALLERIE Xavier RŮŽEK Daniel

  Article in Periodical

  JOURNAL OF VIROLOGY, year: 2019, DOI

• Molecular Epidemiology of Hantaviruses in the Czech Republic

  ZELENÁ Hana STRAKOVÁ Petra HEROLDOVÁ Marta MRÁZEK Jakub KASTL Tomáš ŽÁKOVSKÁ Alena RŮŽEK Daniel SMETANA Jan RUDOLF Ivo

  Article in Periodical

  Emerging Infectious Diseases, year: 2019, volume: 25, edition: 11, DOI

• Viral RNA-dependent RNA polymerase inhibitor 7-deaza-2'-C-methyladenosine prevents death in a mouse model of West Nile virus infection

  EYER Luděk FOJTÍKOVÁ Martina NENCKA Radim RUDOLF Ivo HUBÁLEK Zdeněk RŮŽEK Daniel

  Article in Periodical

  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, year: 2019, volume: 63, edition: 3, DOI

2018

• Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses

  HAVIERNIK Jan ŠTEFÁNIK Michal FOJTÍKOVÁ Martina KALI S TORDO N RUDOLF Ivo HUBÁLEK Zdeněk EYER Luděk RŮŽEK Daniel

  Article in Periodical

  Viruses, year: 2018, DOI

2017

• Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses

  EYER Luděk ZOUHAROVÁ Darina ŠIRMAROVÁ Jana FOJTÍKOVÁ Martina ŠTEFÁNIK Michal HAVIERNIK Jan NENCKA Radim DE CLERCQ Erik RŮŽEK Daniel

  Article in Periodical

  , year: 2017

• Escape of Tick-Borne Flavivirus from 2′-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness

  EYER Luděk KONDO Hirofumi ZOUHAROVÁ Darina HIRANO Minato VALDÉS James J. MUTO Memi KASTL Tomáš KOBAYASHI Shintaro HAVIERNIK Jan IGARASHI Manabu KARIWA Hiroaki Kariwa VACULOVIČOVÁ Markéta ČERNÝ Jiří KIZEK René KRÖGER Andrea LIENENKLAUS Stefan DEJMEK Milan NENCKA Radim PALUS Martin SALÁT Jiří DE CLERCQ Erik YOSHII Kentaro RŮŽEK Daniel

  Article in Periodical

  JOURNAL OF VIROLOGY, year: 2017, DOI

2015

• Analysis of Serum Levels of Cytokines, Chemokines, Growth Factors, and Monoamine Neurotransmitters in Patients With Tick-borne Encephalitis: Identification of Novel Inflammatory Markers With Implications for Pathogenesis

  PALUS Martin FORMANOVÁ Petra SALAT Jiri ZAMPACHOVA Eva ELSTEROVA Jana RŮŽEK Daniel

  Article in Periodical

  JOURNAL OF MEDICAL VIROLOGY, year: 2015, volume: 87, edition: 5, DOI

• Detection of Diverse Novel Bat Astrovirus Sequences in the Czech Republic

  DUFKOVÁ Lucie STRAKOVÁ Petra ŠIRMAROVÁ Jana SALÁT Jiří MOUTELÍKOVÁ Romana CHRUDIMSKÝ Tomáš BARTONIČKA Tomáš NOWOTNY Norbert RŮŽEK Daniel

  Article in Periodical

  VECTOR-BORNE AND ZOONOTIC DISEASES, year: 2015, volume: 15, edition: 8, DOI