Mgr. Karel Souček, Ph.D.

2018

• Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition

  REMŠÍK Ján BINÓ Lucia KAHOUNOVÁ zuzana KHARAISHVILI Gvantsa ŠIMEČKOVÁ Šárka FEDR Radek KUČÍRKOVÁ Tereza LENÁRT Sára MURESAN Ximena Maria SLABÁKOVÁ Eva KNOPFOVÁ Lucia BOUCHAL Jan KRÁL Milan BENEŠ Petr SOUČEK Karel

  Article in Periodical

  Carcinogenesis, year: 2018, volume: 39, edition: 11, DOI

2017

• Alternative mechanisms of miR-34a regulation in cancer

  SLABÁKOVÁ Eva CULIG Z. REMŠÍK Ján SOUČEK Karel

  Article in Periodical

  CELL DEATH & DISEASE, year: 2017, volume: 8, edition: October, DOI

• BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors

  PACULOVÁ Hana KRAMARA Juraj ŠIMEČKOVÁ Šárka FEDR Radek SOUČEK Karel HYLSE Ondřej PARUCH Kamil SVOBODA Marek MISTRÍK Martin KOHOUTEK Jiří

  Article in Periodical

  Tumor Biology, year: 2017, volume: 2017, edition: October, DOI

• Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells

  BOSTROM Johan ŠRÁMKOVÁ Zuzana SALAŠOVÁ Alena JOHARD Helena Anna Dagmar MAHDESSIAN Diana FEDR Radek MARKS Carolyn MEDALOVÁ Jiřina SOUČEK Karel LUNDBERG Emma LINNARSON Sten BRYJA Vítězslav SEKYROVÁ Petra ALTUN Mikael ANDÄNG Michael

  Article in Periodical

  PLOS ONE, year: 2017, volume: 12, edition: 12, DOI

• Diastereoselective Flexible Synthesis of Carbocyclic C Nucleosides

  MAIER Lukáš KHIRSARIYA PrashantKumar HYLSE Ondřej ADLA Santosh Kumar ČERNOVÁ Lenka POLJAK Michal KRAJČOVIČOVÁ Soňa WEIS Erik DRÁPELA Stanislav SOUČEK Karel PARUCH Kamil

  Article in Periodical

  The Journal of Organic Chemistry, year: 2017, volume: 82, edition: 7, DOI

• Flow cytometric analysis of nucleoside transporters activity

  DRÁPELA Stanislav FEDR Radek KHIRSARIYA PrashantKumar PARUCH Kamil SOUČEK Karel

  Conference abstract

  Year: 2017, type: Conference abstract

• Hematological Profile of Untreated or Ionizing Radiation-Exposed Cyclooxygenase-2-Deficient Mice

  HOFER M. HOFEROVA Z. DUŠEK Ladislav SOUČEK Karel GRUZDEV A.

  Article in Periodical

  Physiological research, year: 2017, volume: 66, edition: 4

• Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

  HERŮDKOVÁ Jarmila PARUCH Kamil KHIRSARIYA PrashantKumar SOUČEK Karel KRKOŠKA Martin VONDÁLOVÁ BLANÁŘOVÁ Olga SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Neoplasia, year: 2017, volume: 19, edition: 10, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI

2016

• Cisplatin or LA-12-mediated stimulation of TRAIL-induced apoptosis in human prostate cancer cells involves Bax/Bak-dependent mitochondria activation

  VONDÁLOVÁ BLANÁŘOVÁ Olga HERŮDKOVÁ Jarmila ŠAFAŘÍKOVÁ Barbora KRKOŠKA Martin TOMÁNKOVÁ Silvie PERNICOVÁ Zuzana SOUČEK Karel BOUCHAL Jan KHARAISHVILI G KRÁL M SOVA P HOFMANOVÁ Jiřina KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2016, type: Conference abstract