Informace o projektu
European Human Biomonitoring Initiative
(HBM4EU)
- Kód projektu
- 733032
- Období řešení
- 1/2017 - 6/2022
- Investor / Programový rámec / typ projektu
-
Evropská unie
- Horizon 2020
- Health, demographic change and wellbeing (Societal Challenges)
- Fakulta / Pracoviště MU
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Přírodovědecká fakulta
- prof. RNDr. Jana Klánová, Ph.D.
- Mgr. Ondřej Adamovský, Ph.D.
- Lola Murielle Bajard ép.Esner, Ph.D.
- prof. RNDr. Luděk Bláha, Ph.D.
- doc. RNDr. Pavel Čupr, Ph.D.
- Elena Dominguez Romero, PhD.
- Mgr. Klára Komprdová, Ph.D.
- Ing. Štěpán Koudelka, Ph.D.
- RNDr. Ondřej Májek, Ph.D.
- Lisa Emily Melymuk, Ph.D.
- Chander Kant Negi, Ph.D.
- Mgr. Ondřej Ngo, Ph.D.
- Ing. Šárka Palátová, Ph.D.
- Veronika Janina Schacht, Ph.D.
- Mgr. Libor Šulc, Ph.D.
- Jakub Vinkler, DiS.
- Chiara Maria Vitale, PhD
- Spolupracující organizace
-
Ústav experimentální medicíny AV ČR, v. v. i.
- Odpovědná osoba MUDr. Radim Šrám, DrSc.
- Odpovědná osoba prof. MUDr. Milena Králíčková, Ph.D.
- Odpovědná osoba prof. Ing. Jana Hajšlová, CSc.
- Odpovědná osoba Ing. Adéla Fraňková, Ph.D.
- Odpovědná osoba Gorazd B. Stokin
- Odpovědná osoba RNDr. Ondřej Májek, Ph.D.
- Odpovědná osoba Marike Kolossa-Gehring
The overarching goal of the European Human Biomonitoring Initiative is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies and the evaluation of existing measures.
Key objectives include:
- Harmonizing procedures for human biomonitoring across 26 countries, to provide policy makers with comparable data on human internal exposure to chemicals and mixtures of chemicals at EU level;
- Linking data on internal exposure to chemicals to aggregate external exposure and identifying exposure pathways and upstream sources. Information on exposure pathways is critical to the design of targeted policy measures to reduce exposure;
- Generating scientific evidence on the causal links between human exposure to chemicals and negative health outcomes; and
- Adapting chemical risk assessment methodologies to use human biomonitoring data and account for the contribution of multiple external exposure pathways to the total chemical body burden.
We will achieve these objectives by harmonizing human biomonitoring initiatives in 26 countries, drawing on existing expertise and building new capacities. By establishing National Hubs in each country to coordinate activities, we will create a robust Human Biomonitoring Platform at European level. This initiative contributes directly to the improvement of health and well-being for all age groups, by investigating how exposure to chemicals affects the health of different groups, such as children, pregnant women, foetuses and workers. We will also investigate how factor such as behavior, lifestyle and socio-economic status influence internal exposure to chemicals across the EU population. This knowledge will support policy action to reduce chemical exposure and protect
health.
Publikace
Počet publikací: 51
2023
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Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021)
International Journal of Hygiene and Environmental Health, rok: 2023, ročník: 249, vydání: April 2023, DOI
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Has Regulatory Action Reduced Human Exposure to Flame Retardants?
ENVIRONMENTAL SCIENCE & TECHNOLOGY, rok: 2023, ročník: 57, vydání: 48, DOI
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Identification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study
Toxics, rok: 2023, ročník: 11, vydání: 3, DOI
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Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge
International Journal of Hygiene and Environmental Health, rok: 2023, ročník: 249, vydání: April 2023, DOI
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Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2 '-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant women
International Journal of Hygiene and Environmental Health, rok: 2023, ročník: 250, vydání: May 2023, DOI
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Sugar-sweetened beverages and childhood abnormal adiposity in the Czech Republic - narrative literature review
CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH, rok: 2023, ročník: 31, vydání: 1, DOI
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The Influence of Adiposity Levels on the Relation between Perfluoroalkyl Substances and High Depressive Symptom Scores in Czech Adults
Toxics, rok: 2023, ročník: 11, vydání: 11, DOI
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Time Patterns in Internal Human Exposure Data to Bisphenols, Phthalates, DINCH, Organophosphate Flame Retardants, Cadmium and Polyaromatic Hydrocarbons in Europe
Toxics, rok: 2023, ročník: 11, vydání: 10, DOI
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Time-trends in human urinary concentrations of phthalates and substitutes DEHT and DINCH in Asian and North American countries (2009-2019)
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, rok: 2023, ročník: 33, vydání: 2, DOI
2022
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A large scale multi-laboratory suspect screening of pesticide metabolites in human biomonitoring: From tentative annotations to verified occurrences
Environment International, rok: 2022, ročník: 168, vydání: October 2022, DOI