Mgr. Jan Brezovský, Ph.D.

2016

• HotSpot Wizard 2.0: Automated Design of Site-Specific Mutations and Smart Libraries in Protein Engineering

  BENDL J. ŠTOURAČ Jan ŠEBESTOVÁ Eva VÁVRA Ondřej MUSIL Miloš BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Article in Periodical

  Nucleic Acids Research, year: 2016, volume: 44, edition: W1, DOI

• PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions

  BENDL Jaroslav MUSIL Miloš ŠTOURAČ Jan ZENDULKA Jaroslav DAMBORSKÝ Jiří BREZOVSKÝ Jan

  Article in Periodical

  PLOS COMPUTATIONAL BIOLOGY 12: e100496, year: 2016, volume: 12, edition: 5, DOI

• Role of Tunnels and Gates in Enzymatic Catalysis

  MARQUES Sérgio Manuel BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Chapter of a book

  UNDERSTANDING ENZYMES: FUNCTION, DESIGN, ENGINEERING, AND ANALYSIS, year: 2016, number of pages: 43 s.

• Tools and data services registry: a community effort to document bioinformatics resources

  ISON Jon RAPACKI Kristoffer MENAGER Herve KALAS Matus RYDZA Emil CHMURA Piotr ANTHON Christian BEARD Niall BERKA Karel BOLSER Dan BOOTH Tim BRETAUDEAU Anthony BREZOVSKÝ Jan CASADIO Rita CESARENI Gianni COPPENS Frederik CORNELL Michael CUCCURU Gianmauro DAVIDSEN Kristian DELLA VEDOVA Gianluca DOGAN Tunca DOPPELT-AZEROUAL Olivia EMERY Laura GASTEIGER Elisabeth GATTER Thomas GOLDBERG Tatyana GROSJEAN Marie GRUNING Bjoern HELMER-CITTERICH Manuela IENASESCU Hans IOANNIDIS Vassilios JESPERSEN Martin Closter JIMENEZ Rafael JUTY Nick JUVAN Peter KOCH Maximilian LAIBE Camille LI Jing-Woei LICATA Luana MAREUIL Fabien MICETIC Ivan FRIBORG Rune Mollegaard MORETTI Sebastien MORRIS Chris MOLLER Steffen NENADIC Aleksandra PETERSON Hedi PROFITI Giuseppe RICE Peter ROMANO Paolo RONCAGLIA Paola SAIDI Rabie SCHAFFERHANS Andrea SCHWAMMLE Veit SMITH Callum SPEROTTO Maria Maddalena STOCKINGER Heinz SVOBODOVÁ VAŘEKOVÁ Radka TOSATTO Silvio C. E. DE LA TORRE Victor UVA Paolo VIA Allegra YACHDAV Guy ZAMBELLI Federico VRIEND Gert ROST Burkhard PARKINSON Helen LONGREEN Peter BRUNAK Soren

  Article in Periodical

  Nucleic Acids Research, year: 2016, volume: 44, edition: D1, DOI

2015

• Balancing the Stability-Activity Trade-off by Fine-Tuning Dehalogenase Access Tunnels.

  LIŠKOVÁ Veronika BEDNÁŘ David PRUDNIKOVA T. REZACOVA P. KOUDELÁKOVÁ Táňa ŠEBESTOVÁ Eva KUTA- SMATANOVÁ I., BREZOVSKÝ Jan CHALOUPKOVÁ Radka DAMBORSKÝ Jiří

  Article in Periodical

  ChemCatChem, year: 2015, volume: 7, edition: 4, DOI

• CaverWeb 0,2

  ŠTOURAČ Jan BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Software

  Year: 2015

• FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

  BEDNÁŘ David BEERENS Koen ŠEBESTOVÁ Eva BENDL Jaroslav KHARE S. CHALOUPKOVÁ Radka PROKOP Zbyněk BREZOVSKÝ Jan BAKER D. DAMBORSKÝ Jiří

  Article in Periodical

  PLOS COMPUTATIONAL BIOLOGY, year: 2015, volume: 11, edition: 11, DOI

• HotSpot Wizard 2.0

  ŠTOURAČ Jan BENDL Jaroslav ŠEBESTOVÁ Eva VÁVRA Ondřej MUSIL Miloš BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Software

  Year: 2015

• Mechanism-Based Discovery of Novel Substrates of Haloalkane Dehalogenases using in Silico Screening

  DANIEL Lukáš BURYŠKA Tomáš PROKOP Zbyněk DAMBORSKÝ Jiří BREZOVSKÝ Jan

  Article in Periodical

  Journal of Chemical Information and Modeling, year: 2015, volume: 55, edition: 1, DOI

• PredictSNP 2.0

  BENDL Jaroslav MUSIL Miloš ŠTOURAČ Jan ZENDULKA Jaroslav DAMBORSKÝ Jiří BREZOVSKÝ Jan

  Software

  Year: 2015