Project information
Molecular basis of cell and tissue regulations
- Project Identification
- MSM0021622415
- Project Period
- 1/2005 - 12/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Central European Institute of Technology
- Other MU Faculty/Unit
- Faculty of Medicine
- Keywords
- Cell; genomics; proteomics; biomedicine; gene expression; regulation mechanisms; chromatin structure; structure and interactions of biomolecules
The cell is a system in which each molecule is a component of interaction network. Due to the highly complex interconnection, function of cells and organisms is relatively resistant to failure of individual components of the network. Convergence of thought and methodical approaches which is characteristic for today’s postgenomic era, is a basis for interconnection of research capacities of molecular-biology oriented workgroups of the Masaryk University in the proposed Research Plan (RP). Solving of the RP will proceed in 4 program areas: 1. Regulation mechanisms in animal cells; 2. Functional domains of eukaryotic chromosomes; 3. Genomics and proteomics of regulation circuits in plants; 4. Functional analysis of the genome of clinically and biotechnologically important bacteria. The RP objective is to use approaches of structural biology, functional genomics, proteomics and bioinformatics to elucidate molecular basis of processes which are important from the viewpoint of perspective biomedical and biotechnology applications.
Publications
Total number of publications: 1206
2016
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Způsob ovlivnění lignifikace v rostlinách
Publisher: Úřad průmyslového vlastnictví, state: Czech Republic, patent's number: 306073, year: 2016
2015
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Selection of potential probiotic Lactobacillus strains of human origin for use in dairy industry
European Food Research and Technology, year: 2015, volume: 241, edition: 6, DOI
2014
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Způsob přípravy vzorků pro atomové spektrometrické techniky
Publisher: Úřad průmyslového vlastnictví, state: Czech Republic, patent's number: 304648, year: 2014
2013
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Bacteriophages of Staphylococcus aureus efficiently package various bacterial genes and mobile genetic elements including SCCmec with different frequencies
Environmental Microbiology Reports, year: 2013, volume: 5, edition: 1, DOI
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Differentiation of Lactobacillus Species by ARDRA
Czech Journal of Food Science, year: 2013, volume: 31, edition: 2
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Host response to Borrelia afzelii in BALB/c mice tested by immunoblotting
Annals of Agricultural and Environmental Medicine, year: 2013, volume: 20, edition: 4
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Interactions of plasmacytoid dendritic cells with myeloma plasma cells and gamma/delta T cells in MGUS and multiple myeloma patients
Year: 2013, type: Conference abstract
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Newly discovered genes for resistance to powdery mildew in the subtelomeric region of the short arm of barley chromosome 7H
Czech Journal of Genetics and Plant Breeding, year: 2013, volume: 49, edition: 3
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Nomenclature for Members of the Two-Component Signaling Pathway of Plants
Plant Physiology, year: 2013, volume: 161, edition: 3, DOI
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Single-Base Resolution Sequence-Directed Nucleosome Mapping
Israel Journal of Chemistry, year: 2013, volume: 53, edition: 3-4, DOI